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KMID : 1164220110230010059
Journal of Korean Society for Radiotherapeutic Technology
2011 Volume.23 No. 1 p.59 ~ p.66
Evaluation of Tangential Fields Technique Using TOMO Direct Radiation Therapy after Breast Partial Mastectomy
Kim Mi-Jung

Kim Joo-Ho
Kim Hun-Kyum
Cho Kang-Chul
Jeon Byeong-Cheol
Cho Jung-Heui
Abstract
Purpose: Investigation of the clinical use of tangential fields technique using TOMO direct in comparison to conventional LINAC based radiation therapy after breast partial mastectomy.

Materials and Methods: Treatment plans were created for 3 left-sided breast cancer patients who had radiation therapy after breast partial mastectomy by using wedged tangential fields technique, field in field technique (FIF), TOMO Direct, TOMO Direct intensity modulated radiation therapy (IMRT) under the normalized prescription condition (D90%: 50.4 Gy/28 fx within CTV). Dose volume histogram (DVH) and isodose curve were used to evaluate the dose to the clinical target volume (CTV), organ at risk (OAR). We compared and analyzed dosimetric parameters of CTV and OAR. Dosimetric parameters of CTV are D99,D95 , Dose homogeneity index (DHI:D10/D90 ) and V105,V110 . And dosimetric parameters of OAR are V10,V20 ,V30 ,V40 of the heart and V10,V20 ,V30 of left lung.

Results: Dosimetric results of CTV, the average value of D99,D95 were 47.7¡¾1.1 Gy, 49.4¡¾0.1 Gy from wedged tangential fields technique (W) and FIF (F) were 47.1¡¾0.6 Gy, 49.2¡¾0.4 Gy And it was 49.2¡¾0.4 vs. 48.6¡¾0.8 Gy, 49.9¡¾0.4 vs. 49.5¡¾0.3 Gy for the TOMO Direct (D) and TOMO Direct IMRT (I). The average value of dose homogeneity index was W: 1.1¡¾0.02, F: 1.07¡¾0.02, D:1.03¡¾0.001, I: 1.05¡¾0.02. When we compared the average value of V105,V110 using each technique, it was the highest as 34.6¡¾9.3%,7.5¡¾7.9% for wedged tangential fields technique and the value dropped for FIF as 16.5¡¾14.8%, 2.1¡¾3.5%TOMO direct IMRT as 7.5¡¾8.3%, 0.1¡¾0.1% and the TOMO direct showed the lowest values for both as 0%. Dosimetric results of OAR was no significant difference among each technique.

Conclusion: TOMO direct provides improved target dose homogeneity over wedged tangential field technique. It is no increase the amount of normal tissue volumes receiving low doses, as oppose to IMRT or Helical TOMO IMRT. Also, it simply performs treatment plan procedure than FIF. TOMO Direct is a clinical useful technique for breast cancer patients after partial mastectomy.
KEYWORD
radiation therapy, breast partial mastectomy, tomotherapy
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